A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging
Nandre, Jitendra1; Patil, Samadhan1; Patil, Vijay1; Yu, Fabiao2; Chen, Lingxin2; Sahoo, Suban3; Prior, Timothy4; Redshaw, Carl4; Mahulikar, Pramod1; Patil, Umesh1; Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. [email protected]; [email protected]; [email protected]
发表期刊BIOSENSORS & BIOELECTRONICS
ISSN0956-5663
2014-11-15
卷号61页码:612-617
关键词Fluorescent "turn-on" Sensor Benzo-thiazolo-pyrimidine Fe3++ Ict Pet Live Cells Imaging
DOI10.1016/j.bios.2014.06.017
产权排序[Nandre, Jitendra; Patil, Samadhan; Patil, Vijay; Mahulikar, Pramod; Patil, Umesh] North Maharashtra Univ, Sch Chem Sci, Jalgaon 425001, MS, India; [Yu, Fabiao; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China; [Sahoo, Suban] SV Natl Inst Technol, Dept Appl Chem, Surat 395007, Gujrat, India; [Prior, Timothy; Redshaw, Carl] Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, N Humberside, England
作者部门中科院海岸带环境过程与生态修复重点实验室
英文摘要An electronically active and spectral sensitive fluorescent "turn-on" chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe3+ from aqueous medium. With Fe3+, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (lambda(ex) = 314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe3+ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique. (C) 2014 Elsevier B.V. All rights reserved.; An electronically active and spectral sensitive fluorescent "turn-on" chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe3+ from aqueous medium. With Fe3+, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (lambda(ex) = 314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe3+ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique. (C) 2014 Elsevier B.V. All rights reserved.
文章类型Article
资助机构Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
收录类别SCI
语种英语
关键词[WOS]SENSORS ; POLYMER ; IONS ; FE3+
研究领域[WOS]Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics
WOS记录号WOS:000339692500090
引用统计
被引频次:79[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/8693
专题中国科学院海岸带环境过程与生态修复重点实验室
通讯作者Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China. [email protected]; [email protected]; [email protected]
作者单位1.North Maharashtra Univ, Sch Chem Sci, Jalgaon 425001, MS, India
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai 264003, Peoples R China
3.SV Natl Inst Technol, Dept Appl Chem, Surat 395007, Gujrat, India
4.Univ Hull, Dept Chem, Kingston Upon Hull HU6 7RX, N Humberside, England
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Nandre, Jitendra,Patil, Samadhan,Patil, Vijay,et al. A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging[J]. BIOSENSORS & BIOELECTRONICS,2014,61:612-617.
APA Nandre, Jitendra.,Patil, Samadhan.,Patil, Vijay.,Yu, Fabiao.,Chen, Lingxin.,[email protected].(2014).A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging.BIOSENSORS & BIOELECTRONICS,61,612-617.
MLA Nandre, Jitendra,et al."A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging".BIOSENSORS & BIOELECTRONICS 61(2014):612-617.
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