The invention relates to the fields of foods, cosmetics and biomedicine, in particular to anionized 2-hydroxypropyl trimethyl ammonium chloride chitosan, and a preparation method and application of the anionized 2-hydroxypropyl trimethyl ammonium chloride chitosan. The structural formula of the anionized 2-hydroxypropyl trimethyl ammonium chloride chitosan is shown in formula (1); The method has the advantages of simple reaction, high yield of the target compound and easiness in popularization and industrial application. Experiments prove that the anionized 2-hydroxypropyl trimethyl ammonium chloride chitosan is good in water solubility, has certain bacteriostasis and excellent moisture absorption and retention performances, and can be widely applied to the fields of food, cosmetics and biomedicine. In the formula (1), n represents the degree of polymerization, and the average value ranges from 50 to 1000.
; 宓英其; 张晶晶; 崔静敏; 李青
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