The invention discloses vibrio alginolyticus capable of degrading various sulfanilamide antibiotics and application of the vibrio alginolyticus. The vibrio alginolyticus is screened from estuarine water in an entrance of the guangdang river in Yantai and preserved in the general microbiology center of the China Committee for Culture Collection of Microorganims on June 26, 2019, and the preservation number is : CGMCC No. 18031. The vibrio alginolyticus has the ability of degradation of the sulfanilamide antibiotics, and can degrade the various sulfanilamide antibiotics including sulfadiazine, sulfisoxazole, sulfamethoxazole, sulfadimidine, sulfamonomethoxine, sulfacetamide, sulfamerazine, sulfathiazole and pyridazol. The vibrio alginolyticus capable of degrading the various sulfanilamide antibiotics and application of the vibrio alginolyticus have the beneficial effect that the screened vibrio alginolyticus (with the preservation number being CGMCC No.18031) has great application prospects in the aspect of treatment of polluted water (including fresh water and sea water) which contains the high-concentration sulfanilamide antibiotics.
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