| Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei) | |
| Lyu, Ding1,2,3; Yu, Yang1,2,3; Wang, Quanchao1,3,4; Luo, Zheng1,3,5; Zhang, Qian1,3,5; Zhang, Xiaojun1,2,3; Xiang, Jianhai1,3; Li, Fuhua1,2,3,6 | |
| 发表期刊 | FRONTIERS IN GENETICS
 |
| 2021-04-07 | |
| 卷号 | 12页码:9 |
| 关键词 | GWAS growth trait marker assisted BLUP genetic breeding Litopenaeus vannamei |
| DOI | 10.3389/fgene.2021.611570 |
| 通讯作者 | Li, Fuhua([email protected]) |
| 英文摘要 | The Pacific white shrimp (Litopenaeus vannamei) is the most widely cultured shrimp in the world. A great attention has been paid to improve its body weight (BW) at harvest through genetic selection for decades. Genome-wide association study (GWAS) is a tool to dissect the genetic basis of the traits. In this study, a GWAS approach was conducted to find genes related to BW through genotyping 94,113 single nucleotide polymorphisms (SNPs) in 200 individuals from a breeding population. Four BW-related SNPs located in LG19 and LG39 were identified. Through further candidate gene association analysis, the SNPs in two candidate genes, deoxycytidylate deaminase and non-receptor protein tyrosine kinase, were found to be related with the body weight of the shrimp. Marker-assisted best linear unbiased prediction (MA-BLUP) based on the SNPs in these two genes was used to estimate the breeding values, and the result showed that the highest prediction accuracy of MA-BLUP was increased by 9.4% than traditional BLUP. These results will provide useful information for the marker-assisted breeding in L. vannamei. |
| 资助机构 | Strategic Priority Research Program of the Chinese Academy of Sciences ; National Key R&D Program of China ; Agricultural Variety Improvement Project of Shandong Province ; China Agriculture Research System-48 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 研究领域[WOS] | Genetics & Heredity |
| WOS记录号 | WOS:000641715100001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/27303 |
| 专题 | 海岸带生物学与生物资源利用重点实验室 |
| 通讯作者 | Li, Fuhua |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lyu, Ding,Yu, Yang,Wang, Quanchao,et al. Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)[J]. FRONTIERS IN GENETICS,2021,12:9. |
| APA | Lyu, Ding.,Yu, Yang.,Wang, Quanchao.,Luo, Zheng.,Zhang, Qian.,...&Li, Fuhua.(2021).Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei).FRONTIERS IN GENETICS,12,9. |
| MLA | Lyu, Ding,et al."Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)".FRONTIERS IN GENETICS 12(2021):9. |
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