Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.
Fang, ST; Yan, BF; Yang, CY; Miao, FP; Ji, NY
发表期刊JOURNAL OF ANTIBIOTICS
ISSN0021-8820
2017-11
卷号70期号:11页码:1043-1046
关键词ANALOGS
研究领域Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
DOI10.1038/ja.2017.109
产权排序[Fang, Sheng-Tao; Yang, Cui-Yun; Miao, Feng-Ping; Ji, Nai-Yun] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; [Yan, Bing-Fei] Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要Hymerhabdrin A (1), a diterpenoid possessing a novel 6/6/5 fused-ring skeleton, together with four known sterols were isolated from an intertidal marine sponge Hymerhabdia sp. Their structures were elucidated by extensive spectroscopic methods, and the relative and absolute configurations of 1 were determined by NOESY analysis and electronic circular dichrosim calculations, respectively. Hymerhabdrin A (1) exhibited significant antifouling activity against Balanus amphitrite larval with LC50 (lethal concentration 50) value of 3.6 mu g ml(-1).
文章类型Article
资助机构National Natural Science Foundation of China [21202198]
收录类别SCI
语种英语
关键词[WOS]ANALOGS
研究领域[WOS]Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS记录号WOS:000413920300002
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cn/handle/133337/24353
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China;
2.Yantai Univ, Chem & Chem Engn Coll, Yantai, Peoples R China
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Fang, ST,Yan, BF,Yang, CY,et al. Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.[J]. JOURNAL OF ANTIBIOTICS,2017,70(11):1043-1046.
APA Fang, ST,Yan, BF,Yang, CY,Miao, FP,&Ji, NY.(2017).Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp..JOURNAL OF ANTIBIOTICS,70(11),1043-1046.
MLA Fang, ST,et al."Hymerhabdrin A, a novel diterpenoid with antifouling activity from the intertidal sponge Hymerhabdia sp.".JOURNAL OF ANTIBIOTICS 70.11(2017):1043-1046.
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