Isolation, synthesis, and radical-scavenging activity of rhodomelin A, a ureidobromophenol from the marine red alga Rhodomela confervoides

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	Isolation, synthesis, and radical-scavenging activity of rhodomelin A, a ureidobromophenol from the marine red alga Rhodomela confervoides
	Li K(李可)
发表期刊	Organic Letters
ISSN	1523-7060
	2018
卷号	20 期号:2 页码:417-420
关键词	Antioxidant Activity Bromophenols Bromophenols
英文摘要	A novel ureidobromophenol, rhodomelin A (1), was characterized from Rhodomela confervoides. Its structure was elucidated by spectroscopic analysis. Both enantiomers of 1 were synthesized using a convergent strategy starting from d/l-pyroglutamic acids, respectively, allowing assignment of the R-configuration for the naturally occurring isomer by chiral HPLC analysis. Rhodomelin A represents the first example of a naturally occurring ureidopyrrolidone alkaloid incorporating a γ-aminobutyric acid unit. The scavenging activity of 1 toward DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate)) radicals was assayed.
文章类型	Article
收录类别	SCI
关键词[WOS]	Antioxidant Activity ; Bromophenols ; Bromophenols
WOS记录号	WOS:000423252400026
引用统计	被引频次：23[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/24118
专题	个人在本单位外知识产出
作者单位	Institute of Oceanology, Chinese Academy of Sciences
推荐引用方式 GB/T 7714	Li K. Isolation, synthesis, and radical-scavenging activity of rhodomelin A, a ureidobromophenol from the marine red alga Rhodomela confervoides[J]. Organic Letters,2018,20(2):417-420.
APA	Li K.(2018).Isolation, synthesis, and radical-scavenging activity of rhodomelin A, a ureidobromophenol from the marine red alga Rhodomela confervoides.Organic Letters,20(2),417-420.
MLA	Li K."Isolation, synthesis, and radical-scavenging activity of rhodomelin A, a ureidobromophenol from the marine red alga Rhodomela confervoides".Organic Letters 20.2(2018):417-420.

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