| Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group | |
Hu, Yunxia1,2 ; Zhang, Jun3; Yu, Chunwei3; Li, Qing1; Dong, Fang1; Wang, Gang1; Guo, Zhanyong1; Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. [email protected]
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| 发表期刊 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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| ISSN | 0141-8130 |
| 2014-09-01 | |
| 卷号 | 70页码:44-49 |
| 关键词 | Inulin Derivatives Antioxidant Properties Amino-pyridines |
| DOI | 10.1016/j.ijbiomac.2014.06.024 |
| 产权排序 | [Hu, Yunxia; Li, Qing; Dong, Fang; Wang, Gang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Hu, Yunxia] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Zhang, Jun; Yu, Chunwei] Hainan Med Coll, Sch Trop & Lab Med, Environm Monitoring Lab, Haikou 571199, Peoples R China |
| 作者部门 | 海岸带生物学与生物资源利用所重点实验室 |
| 英文摘要 | A series of novel inulin derivatives were synthesized via reaction of chloracetyl inulin (CAR) with amino-pyridines, including 2-(2-amino-pyridyl)acetyl inulin chloride (2APAIL), 2-(3-amino-pyridyl)acetyl inulin chloride (3APAIL), 2-(4-amino-pyridyl)acetyl inulin chloride (4APAIL), 2-(2,3-diaminopyridyl)acetyl inulin chloride (2,3DAPAIL), and 2-(3,4-diamino-pyridyl)acetyl inulin (3,4DAPAIL). The antioxidant property of the products and 2-pyridylacetyl inulin chloride (PAIL) against hydroxyl radicals ((OH)-O-center dot), superoxide radicals (O-2(center dot)), and DPPH radicals (DPPH center dot) were evaluated in vitro, respectively. Results showed that 4APAIL and 3,4DAPAIL exhibited remarkable improvement on scavenging (OH)-O-center dot and DPPH center dot, which can scavenge the radical of (OH)-O-center dot completely at 0.4 mg/mL. Besides, the scavenging activity of 2,3DAPAIL to O-2(center dot) was excellent among all of the tested samples, reaching 85% at 1.6 mg/mL. These data indicate that all of the inulin derivatives have better antioxidant activities than inulin, and the scavenging effect indices are affected by the number and position of the amino group on pyridine grafted to the inulin derivatives. (C) 2014 Elsevier B.V. All rights reserved. |
| 文章类型 | Article |
| 资助机构 | 12th Five-Year Science and Technology Plan for Agriculture 2012BAD32B09 ; Science and Technology Project of Yantai 20121321 ; Taishan Scholar Program of Shandong Province |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | IN-VITRO ; ANTIFUNGAL ACTIVITY ; CHITOSAN DERIVATIVES ; POLYSACCHARIDES ; FRUCTANS ; DESIGN ; CHITIN |
| 研究领域[WOS] | Biochemistry & Molecular Biology |
| WOS记录号 | WOS:000342478800006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/8531 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 通讯作者 | Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. [email protected] |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Hainan Med Coll, Sch Trop & Lab Med, Environm Monitoring Lab, Haikou 571199, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Yunxia,Zhang, Jun,Yu, Chunwei,et al. Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2014,70:44-49. |
| APA | Hu, Yunxia.,Zhang, Jun.,Yu, Chunwei.,Li, Qing.,Dong, Fang.,...&Guo, ZY .(2014).Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,70,44-49. |
| MLA | Hu, Yunxia,et al."Synthesis, characterization, and antioxidant properties of novel inulin derivatives with amino-pyridine group".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 70(2014):44-49. |
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