| Dietary Exposure Estimates of 14 Trace Elements in Xuanwei and Fuyuan, Two High Lung Cancer Incidence Areas in China | |
Zhang, Linlin2; Lv, Jungang1; Liao, Chunyang3
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| 发表期刊 | BIOLOGICAL TRACE ELEMENT RESEARCH
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| ISSN | 0163-4984 |
| 2012-06-01 | |
| 卷号 | 146期号:3页码:287-292 |
| 关键词 | Trace Elements Lung Cancer Dietary Intake Icp-ms |
| 产权排序 | [Lv, Jungang] Supreme Peoples Procuratorate, Procuratoral Technol & Informat Res Ctr, Beijing 100040, Peoples R China; [Zhang, Linlin] Natl Environm Monitoring Ctr, Beijing 100012, Peoples R China; [Liao, Chunyang] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China |
| 通讯作者 | Lv, JG (reprint author), Supreme Peoples Procuratorate, Procuratoral Technol & Informat Res Ctr, Beijing 100040, Peoples R China.,[email protected] |
| 英文摘要 | Xuanwei and Fuyuan, located in the Yunnan province in southwest of China, are known to have a strikingly high incidence of lung cancer. Among the many factors that have been explored, the association between lung cancer and trace elements has not received enough attention. In this study, dietary samples were collected from 60 families of the lung cancer and control groups and abundances of 14 trace elements were determined using inductively coupled-plasma mass spectroscopy. Accuracy and sensitivity of the method were demonstrated by analyzing national standard reference materials. The results showed that the dietary intake of the trace elements contributed 96.6% of total intake. Among the 14 elements tested, cadmium and titanium were found to be present at a significantly higher level in the food consumed by the cancer group than by the control group. The intake of selenium by the population living in the areas is much lower than what it should be, with the people in the cancer group experiencing even more severe selenium deficiency. In addition, in both groups, the intakes of several essential elements (iron, copper, and zinc) from food and the drinking water were found to be significantly lower than required according to the Chinese Dietary Reference Intakes. The present study of the relationship between trace element intakes of lung cancer cases and controls provides important information urgently needed for the assessment of lung cancer risk of healthy subjects. The study also gives rational dietary suggestions to local residents which is important to the early diagnosis and pretreatment of lung cancer.; Xuanwei and Fuyuan, located in the Yunnan province in southwest of China, are known to have a strikingly high incidence of lung cancer. Among the many factors that have been explored, the association between lung cancer and trace elements has not received enough attention. In this study, dietary samples were collected from 60 families of the lung cancer and control groups and abundances of 14 trace elements were determined using inductively coupled-plasma mass spectroscopy. Accuracy and sensitivity of the method were demonstrated by analyzing national standard reference materials. The results showed that the dietary intake of the trace elements contributed 96.6% of total intake. Among the 14 elements tested, cadmium and titanium were found to be present at a significantly higher level in the food consumed by the cancer group than by the control group. The intake of selenium by the population living in the areas is much lower than what it should be, with the people in the cancer group experiencing even more severe selenium deficiency. In addition, in both groups, the intakes of several essential elements (iron, copper, and zinc) from food and the drinking water were found to be significantly lower than required according to the Chinese Dietary Reference Intakes. The present study of the relationship between trace element intakes of lung cancer cases and controls provides important information urgently needed for the assessment of lung cancer risk of healthy subjects. The study also gives rational dietary suggestions to local residents which is important to the early diagnosis and pretreatment of lung cancer. |
| 文章类型 | Article |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | RISK ; STATISTICS ; CADMIUM ; WEI |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| WOS记录号 | WOS:000303407900001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/6177 |
| 专题 | 中国科学院烟台海岸带研究所知识产出 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 作者单位 | 1.Supreme Peoples Procuratorate, Procuratoral Technol & Informat Res Ctr, Beijing 100040, Peoples R China 2.Natl Environm Monitoring Ctr, Beijing 100012, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Linlin,Lv, Jungang,Liao, Chunyang. Dietary Exposure Estimates of 14 Trace Elements in Xuanwei and Fuyuan, Two High Lung Cancer Incidence Areas in China[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2012,146(3):287-292. |
| APA | Zhang, Linlin,Lv, Jungang,&Liao, Chunyang.(2012).Dietary Exposure Estimates of 14 Trace Elements in Xuanwei and Fuyuan, Two High Lung Cancer Incidence Areas in China.BIOLOGICAL TRACE ELEMENT RESEARCH,146(3),287-292. |
| MLA | Zhang, Linlin,et al."Dietary Exposure Estimates of 14 Trace Elements in Xuanwei and Fuyuan, Two High Lung Cancer Incidence Areas in China".BIOLOGICAL TRACE ELEMENT RESEARCH 146.3(2012):287-292. |
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