| Potentiometric sensor for sensitive and selective detection of heparin | |
Chen, Yan1,2; Liang, Rong Ning1; Qin, Wei1
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| 发表期刊 | CHINESE CHEMICAL LETTERS
 |
| ISSN | 1001-8417 |
| 2012-02-01 | |
| 卷号 | 23期号:2页码:233-236 |
| 关键词 | Potentiometry Sensing Element Heparin Protamine Polyion Sensor |
| 产权排序 | [Chen, Yan; Liang, Rong Ning; Qin, Wei] Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Chen, Yan] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 通讯作者 | Qin, W (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. [email protected] |
| 作者部门 | 环境化学实验室 |
| 英文摘要 | A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved.; A polymeric membrane ion-selective electrode for determination of heparin is described in this paper. Protamine is incorporated into the organic membrane phase and functions as sensing element for selective recognition of heparin. The proposed membrane electrode exhibits high selectivity for heparin over lipophilic anions such as thiocyanide and salicylate. The potentiometric response to the concentration of heparin is linear in the range of 0.01-0.4 U/mL and a lower detection limit of 0.005 U/mL can be achieved. (C) 2011 Wei Qin. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China[41176081]; Outstanding Youth Natural Science Foundation of Shandong Province[JQ200814]; Taishan Scholar Program of Shandong Province[TS20081159] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | MEMBRANE-ELECTRODE ; BIOANALYTICAL APPLICATIONS ; ELECTROCHEMICAL SENSOR |
| 研究领域[WOS] | Chemistry |
| WOS记录号 | WOS:000299917200028 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/5527 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室 |
| 作者单位 | 1.Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yan,Liang, Rong Ning,Qin, Wei. Potentiometric sensor for sensitive and selective detection of heparin[J]. CHINESE CHEMICAL LETTERS,2012,23(2):233-236. |
| APA | Chen, Yan,Liang, Rong Ning,&Qin, Wei.(2012).Potentiometric sensor for sensitive and selective detection of heparin.CHINESE CHEMICAL LETTERS,23(2),233-236. |
| MLA | Chen, Yan,et al."Potentiometric sensor for sensitive and selective detection of heparin".CHINESE CHEMICAL LETTERS 23.2(2012):233-236. |
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