| A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities | |
Zhang, Hongyu1,2; Wang, Hongpeng3; Cui, Hongli1; Li, Zonggang4; Xie, Zeping1; Pu, Yang1; Li, Fuchao5; Qin, Song1
| |
| 发表期刊 | MARINE DRUGS
 |
| ISSN | 1660-3397 |
| 2011-09-01 | |
| 卷号 | 9期号:9页码:1502-1509 |
| 关键词 | Streptomyces Anthracene Structure Establishment Cytotoxicity |
| 产权排序 | [Zhang, Hongyu; Cui, Hongli; Xie, Zeping; Pu, Yang; Qin, Song] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, Hongyu] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China; [Wang, Hongpeng] Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany; [Li, Zonggang] China Agr Univ, Yantai Inst China Agr Univ, Yantai 264670, Peoples R China; [Li, Fuchao] Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 通讯作者 | Qin, S (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 作者部门 | 生物资源实验室 |
| 英文摘要 | A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549.; A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3, 4-tetrahydro-benz[alpha]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D- and 2D-NMR ((1)H-(1)H COSY, HMBC, HSQC and NOESY) experiments. 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[alpha]anthracene showed cytotoxicity against human lung adenocarcinoma cell line A549. |
| 文章类型 | Article |
| 资助机构 | CAS, Chinese Academy of Sciences[JQ200914, KSCX2-YW-G-073, KZCX2-YW-216, KZCX2-YW-209]; National Natural Science Foundation of China[31000037] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | ANTIBIOTICS |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| WOS记录号 | WOS:000298927500005 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/5348 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany 4.China Agr Univ, Yantai Inst China Agr Univ, Yantai 264670, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hongyu,Wang, Hongpeng,Cui, Hongli,et al. A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities[J]. MARINE DRUGS,2011,9(9):1502-1509. |
| APA | Zhang, Hongyu.,Wang, Hongpeng.,Cui, Hongli.,Li, Zonggang.,Xie, Zeping.,...&Qin, Song.(2011).A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities.MARINE DRUGS,9(9),1502-1509. |
| MLA | Zhang, Hongyu,et al."A New Anthracene Derivative from Marine Streptomyces sp W007 Exhibiting Highly and Selectively Cytotoxic Activities".MARINE DRUGS 9.9(2011):1502-1509. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| A New Anthracene Der（197KB） | 开放获取 | -- | 浏览 请求全文 | |||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论