| Fluorescent probe for copper(II) ion based on a rhodamine spirolactame derivative, and its application to fluorescent imaging in living cells | |
Yu, Chunwei1,2,3,7; Zhang, Jun4,5; Li, Jinhua1,2,3 ; Liu, Ping1,2,3; Wei, Peihai6; Chen, Lingxin1,2,3
| |
| 发表期刊 | MICROCHIMICA ACTA
 |
| ISSN | 0026-3672 |
| 2011-09-01 | |
| 卷号 | 174期号:3-4页码:247-255 |
| 关键词 | Copper(Ii) Ions Fluorescent Probe Fluorescence Enhancement Rhodamine Derivatives Fluorescence Imaging Living Cells |
| 产权排序 | [Yu, CW; Li, JH; Liu, P; Chen, LX] CAS, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Yu, CW; Li, JH; Liu, P; Chen, LX] Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Yu, CW; Li, JH; Liu, P; Chen, LX] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, J] Hainan Med Univ, Sch Trop, Haikou 571101, Peoples R China; [Zhang, J] Hainan Med Univ, Lab Med, Haikou 571101, Peoples R China; [Wei, PH] Qilu Normal Univ, Dept Chem, Jinan 250013, Peoples R China; [Yu, CW] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 通讯作者 | Chen, LX, CAS, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. [email protected] |
| 作者部门 | 环境化学实验室 |
| 英文摘要 | A fluorescent probe for Cu(II) ion is presented. It is based on the rhodamine fluorophore and exhibits high selectivity and sensitivity for Cu(II) ion in aqueous methanol (2:8, v/v) at pH 7.0. The response is based on a ring opening reaction and formation of a strongly fluorescent 1:1 complex. The response is reversible and linear in the range between 50 nM and 900 nM, with a detection limit of 7.0 nM. The probe was successfully applied to fluorescent imaging of Cu(II) ions in HeLa cells.; A fluorescent probe for Cu(II) ion is presented. It is based on the rhodamine fluorophore and exhibits high selectivity and sensitivity for Cu(II) ion in aqueous methanol (2:8, v/v) at pH 7.0. The response is based on a ring opening reaction and formation of a strongly fluorescent 1:1 complex. The response is reversible and linear in the range between 50 nM and 900 nM, with a detection limit of 7.0 nM. The probe was successfully applied to fluorescent imaging of Cu(II) ions in HeLa cells. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China[20975089]; Department of Science and Technology of Shandong Province of China[2008GG20005005]; Chinese Academy of Sciences[KZCX2-EW-206]; Shandong Province Doctor Fund[2008BS04031] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | AQUEOUS-SOLUTION ; ON FLUORESCENT ; CU2+ IONS ; OFF-ON ; SENSITIVITY ; CHEMOSENSOR ; SELECTIVITY ; CHEMODOSIMETER ; COMPLEXES ; HYDRAZIDE |
| 研究领域[WOS] | Chemistry |
| WOS记录号 | WOS:000293964400007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/5103 |
| 专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 中国科学院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.CAS, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 2.Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 4.Hainan Med Univ, Sch Trop, Haikou 571101, Peoples R China 5.Hainan Med Univ, Lab Med, Haikou 571101, Peoples R China 6.Qilu Normal Univ, Dept Chem, Jinan 250013, Peoples R China 7.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Chunwei,Zhang, Jun,Li, Jinhua,et al. Fluorescent probe for copper(II) ion based on a rhodamine spirolactame derivative, and its application to fluorescent imaging in living cells[J]. MICROCHIMICA ACTA,2011,174(3-4):247-255. |
| APA | Yu, Chunwei,Zhang, Jun,Li, Jinhua,Liu, Ping,Wei, Peihai,&Chen, Lingxin.(2011).Fluorescent probe for copper(II) ion based on a rhodamine spirolactame derivative, and its application to fluorescent imaging in living cells.MICROCHIMICA ACTA,174(3-4),247-255. |
| MLA | Yu, Chunwei,et al."Fluorescent probe for copper(II) ion based on a rhodamine spirolactame derivative, and its application to fluorescent imaging in living cells".MICROCHIMICA ACTA 174.3-4(2011):247-255. |
| 条目包含的文件 | 下载所有文件 | |||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Fluorescent probe fo（372KB） | 开放获取 | -- | 浏览 下载 | |||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论