Recent advances in molecular imprinting technology: current status, challenges and highlighted applications

YIC-IR > 中国科学院海岸带环境过程与生态修复重点实验室 > 海岸带环境工程技术研究与发展中心

	Recent advances in molecular imprinting technology: current status, challenges and highlighted applications
	Chen, Lingxin1 ; Xu, Shoufang 1,2; Li, Jinhua1
发表期刊	CHEMICAL SOCIETY REVIEWS
ISSN	0306-0012
	2011
卷号	40 期号:5 页码:2922-2942
关键词	Solid-phase Extraction Performance Liquid-chromatography Restricted-access Materials Functionalized Silica-gel Beta-cyclodextrin Polymer Precipitation Polymerization Water Samples Ionic Liquid Selective Extraction Protein Recognition
产权排序	[Chen, Lingxin; Xu, Shoufang; Li, Jinhua] Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Xu, Shoufang] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
通讯作者	Chen, LX, Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R [email protected]
作者部门	环境化学实验室
英文摘要	Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).; Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).
文章类型	Review
资助机构	Chinese Academy of Sciences (IOCAS) [072715]; CAS/SAFEA
收录类别	SCI
语种	英语
关键词[WOS]	SOLID-PHASE EXTRACTION ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; RESTRICTED-ACCESS MATERIALS ; FUNCTIONALIZED SILICA-GEL ; BETA-CYCLODEXTRIN POLYMER ; PRECIPITATION POLYMERIZATION ; WATER SAMPLES ; IONIC LIQUID ; SELECTIVE EXTRACTION ; PROTEIN RECOGNITION
研究领域[WOS]	Chemistry
WOS记录号	WOS:000289630700046
引用统计	被引频次：1469[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/4853
专题	中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心中国科学院海岸带环境过程与生态修复重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Lingxin,Xu, Shoufang,Li, Jinhua. Recent advances in molecular imprinting technology: current status, challenges and highlighted applications[J]. CHEMICAL SOCIETY REVIEWS,2011,40(5):2922-2942.
APA	Chen, Lingxin,Xu, Shoufang,&Li, Jinhua.(2011).Recent advances in molecular imprinting technology: current status, challenges and highlighted applications.CHEMICAL SOCIETY REVIEWS,40(5),2922-2942.
MLA	Chen, Lingxin,et al."Recent advances in molecular imprinting technology: current status, challenges and highlighted applications".CHEMICAL SOCIETY REVIEWS 40.5(2011):2922-2942.

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