Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives

doi:10.1016/j.trac.2021.116371

	Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives
	Qin, Xiaoxiao 1; Liu, Jiajing 1; Zhang, Zhong 1,2; Li, Jinhua2 ; Yuan, Li 1; Zhang, Zhiyang2 ; Chen, Lingxin2,3,4
发表期刊	TRAC-TRENDS IN ANALYTICAL CHEMISTRY
ISSN	0165-9936
	2021-10-01
卷号	143 页码:15
关键词	Microfluidic paper-based chips Rapid detection Food safety Portable device Pathogen
DOI	10.1016/j.trac.2021.116371
通讯作者	Zhang, Zhong([email protected]) ; Chen, Lingxin([email protected])
英文摘要	Microfluidic paper-based chips (mu PCs) are micro-laboratory analysis systems that use paper instead of traditional microfluidic substrate materials and miniaturize biochemical reactions. Based on traditional 2D mu PCs, the novel mu PCs are innovative 3D structure chips that are realized by fluid channel construction, channel microvalve, folding and other fluid control methods. In recent years, mu PCs have developed rapidly in terms of design and integration and have been widely used in food safety, environmental residue pollution, pathogen detection and other applications. Due to their advantages of low cost, portability and satisfactory thermal stability, they have unique potential in the field of rapid detection. Herein, based on the detailed preparation, we focus on the selection of the paper substrate, microfluidic chip hydrophilic/hydrophobic processing and substrate modification. We highlight the latest research progress of mu PCs in rapid detection from 2014 to 2021, and discuss the remaining challenges and future perspectives for further development. (C) 2021 Elsevier B.V. All rights reserved.
资助机构	National Natural Science Foundation of China ; Shaanxi Province Key Research and Development Project ; Postdoctoral Program of Shaanxi Province ; Fundamental Research Fund of the Central University ; Taishan Scholar Project Special Funding
收录类别	SCI
语种	英语
关键词[WOS]	LOW-COST ; FLUORESCENCE DETECTION ; MULTIPLEXED DETECTION ; SENSITIVE DETECTION ; BETA-AGONISTS ; DEVICES ; PLATFORM ; FABRICATION ; SENSOR ; ASSAY
研究领域[WOS]	Chemistry
WOS记录号	WOS:000711411900027
引用统计	被引频次：111[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/37618
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
通讯作者	Zhang, Zhong; Chen, Lingxin
作者单位	1.Shaanxi Normal Univ, Shaanxi Engn Lab Food Green Proc & Safety Control, Engn Res Ctr High Value Utilizat Western Fruit Re, Coll Food Engn & Nutr Sci,Minist Educ, Xian 710062, Shaanxi, Peoples R China 2.Chinese Acad Sci, Shandong Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Rem, Yantai 264003, Shandong, Peoples R China 3.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Peoples R China 4.Qingdao Univ Technol, Sch Environm & Municipal Engn, Qingdao 266033, Peoples R China
推荐引用方式 GB/T 7714	Qin, Xiaoxiao,Liu, Jiajing,Zhang, Zhong,et al. Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2021,143:15.
APA	Qin, Xiaoxiao.,Liu, Jiajing.,Zhang, Zhong.,Li, Jinhua.,Yuan, Li.,...&Chen, Lingxin.(2021).Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,143,15.
MLA	Qin, Xiaoxiao,et al."Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 143(2021):15.