Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans

doi:10.1016/j.ijbiomac.2024.136045

	Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans
	Zhao, Yang 1,3; Yuan, Ke 1; Ning, Junhao 1; Liu, Guilong 4; Xu, Xin 4; Wang, Chunde 1; Lu, Xia2
发表期刊	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN	0141-8130
	2024-11-01
卷号	280 页码:12
关键词	Lipases Antioxidases Nutrient restriction Longevity Argopecten scallops
DOI	10.1016/j.ijbiomac.2024.136045
通讯作者	Wang, Chunde([email protected]) ; Lu, Xia([email protected])
英文摘要	Nutrient restriction (NR) extends lifespan in many species. High latitudes are characterized by cold-water temperature and food limitations, where bivalves may mimic NR like vertebrates, which could result in a prolonged life expectancy. The long-lived Peruvian scallop (7-10 years) distributes naturally at relatively higher latitudes than the annual bay scallop. However, the relationship and the mechanism underlying the food availability and lifespan are unclear in bivalves. In this study, the genetic response to NR was first investigated in bivalves with distinct lifespans. Peruvian scallops persistently responded to NR mainly via metabolic pathways, but that began to play roles in bay scallops after 56 days. Significant down-regulated expression of long-chain saturated fatty acid synthetase in both two scallops and increased expression of SCD5 and LIPN2 in Peruvian scallops might contribute to MUFA accumulation under NR. SOD1 was more highly expressed in Peruvian scallops than in bay scallops under NR, and strong autophagy was detected only in Peruvian scallops. Peruvian scallops presented much lower MDA levels and higher SOD1 activities than bay scallops. These findings help us understanding the role of lipases and antioxidases in longevity of bivalves, and provide potential biomarkers for breeding long-lived larger scallops.
资助机构	National Natural Science Foundation of China ; National Key Research and Development Program of China ; Scientific and Technological Project of Yantai, Shandong Province ; Earmarked Fund for Shandong Modern Agro-Industry Technology Research System
收录类别	SCI
语种	英语
关键词[WOS]	CALORIC RESTRICTION ; EXTREME LONGEVITY ; GENE-EXPRESSION ; GRADED-LEVELS ; BAY SCALLOP ; METABOLISM ; PLASTICITY ; TELOMERES ; AUTOPHAGY ; STRESS
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS记录号	WOS:001328215300001
引用统计
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/36501
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Wang, Chunde; Lu, Xia
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res & Dev Ctr Efficient Utilizat Coastal Bioresour, Yantai 264003, Shandong, Peoples R China 2.Yantai Univ, Sch Ocean, Yantai 264005, Shandong, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yantai Spring Sea AquaSeed Ltd, Yantai 264006, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Yang,Yuan, Ke,Ning, Junhao,et al. Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2024,280:12.
APA	Zhao, Yang.,Yuan, Ke.,Ning, Junhao.,Liu, Guilong.,Xu, Xin.,...&Lu, Xia.(2024).Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,280,12.
MLA	Zhao, Yang,et al."Potential roles of lipases and antioxidases on longevity under nutrient restriction in two Argopecten scallops with distinct lifespans".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 280(2024):12.