Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus <i>Chaetomium globosum</i> SD-347

doi:10.1039/d4ob00449c

	*Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum* SD-347**
	Li, Xiao-Dong 1,2,3; Li, Xiao-Ming 1; Wang, Bin-Gui 1,3,4; Li, Xin 1,4
发表期刊	ORGANIC & BIOMOLECULAR CHEMISTRY
ISSN	1477-0520
	2024-04-29
页码	7
DOI	10.1039/d4ob00449c
通讯作者	Wang, Bin-Gui([email protected]) ; Li, Xin([email protected])
英文摘要	Two new sesterterpenoids, sesterchaetins A and B (1 and 2), and two new diepoxide polyketides, chaetoketoics A and B (3 and 4), were characterized from the culture extract of Chaetomium globosum SD-347, a fungal strain derived from deep sea-sediment. Their structures and absolute configurations were unambiguously determined by detailed NMR, mass spectra, and X-ray crystallographic analysis. Compounds 1 and 2 contained a distinctive 5/8/6/5 tetracyclic carbon-ring-system, which represented a rarely occurring natural product framework. The new isolates 1-4 exhibited selective antimicrobial activities against human and aquatic pathogenic bacteria and plant-pathogenic fungi.
资助机构	Qingdao National Laboratory for Marine Science and Technology ; Shandong Special Fund for Qingdao National Laboratory for Marine Science and Technology ; National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation ; Youth Innovation Promotion Association CAS ; National Major Science and Technology Infrastructure from the Chinese Academy of Sciences
收录类别	SCI
语种	英语
关键词[WOS]	ENDOPHYTIC FUNGUS ; NATURAL-PRODUCTS ; A-D ; METABOLITES ; CHAETOGLOBOSIN ; GENES
研究领域[WOS]	Chemistry
WOS记录号	WOS:001216632600001
引用统计
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/36088
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Wang, Bin-Gui; Li, Xin
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 4.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China
推荐引用方式 GB/T 7714	Li, Xiao-Dong,Li, Xiao-Ming,Wang, Bin-Gui,et al. Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2024:7.
APA	Li, Xiao-Dong,Li, Xiao-Ming,Wang, Bin-Gui,&Li, Xin.(2024).Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347.ORGANIC & BIOMOLECULAR CHEMISTRY,7.
MLA	Li, Xiao-Dong,et al."Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347".ORGANIC & BIOMOLECULAR CHEMISTRY (2024):7.