Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea

doi:10.1007/s11783-024-1868-4

	Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea
	Lu, Jian1 ; Wu, Jun 2; Zhang, Cui 1; Wang, Jianhua1 ; He, Xia 3
发表期刊	FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING
ISSN	2095-2201
	2024-09-01
卷号	18 期号:9 页码:12
关键词	The South China Sea Antibiotic resistance genes Mobile genetic element Source apportionment
DOI	10.1007/s11783-024-1868-4
通讯作者	Wu, Jun([email protected])
英文摘要	Antibiotic resistance genes (ARGs) might have great effect on ecological security and human health. Oceans are important reservoirs that receive tremendous amounts of pollutants globally. However, information on the proliferation of ARGs in seawater is still limited. This study performed field sampling to investigate the occurrence and distribution of ARGs in seawater of the South China Sea, which is the deepest and largest sea in China. The results showed that the total absolute abundances of ARGs in seawater samples ranged from 2.1 x 103 to 2.3 x 104 copies/mL, with an of 5.0 x 103 copies/mL and a range of 2.2 x 103-1.8 x 104 copies/mL for those with mobile genetic elements (MGEs). Genes resistant to multidrug, aminoglycoside, tetracycline, and fluoroquinolone antibiotics accounted for 77.3%-88.6% of total ARGs in seawater. Proteobacteria and Cyanobacteria represented 32.1%-56.2% and 30.4%-49.5% of microbial community, respectively. Prochlorococcus_MIT9313 and Clade_la were the prevalent genera in seawater of the South China Sea. Complex co-occurrence relationship existed among ARGs, MGEs, and bacteria. Anthropogenic activities had critical influence on ARGs and MGEs. Hospital wastewater, wastewater treatment plant effluent, sewage, aquaculture tailwater, and runoff were determined as the important sources of ARGs in seawater of the South China Sea based on positive matrix factorization analysis.
资助机构	National Natural Science Foundation of China ; Taishan Scholars Program, Shandong Provincial Natural Science Foundation ; Research Program of CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation ; Key R&D Program of Shandong Province, China
收录类别	SCI
语种	英语
关键词[WOS]	DIVERSITY
研究领域[WOS]	Engineering ; Environmental Sciences & Ecology
WOS记录号	WOS:001253360900002
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/35896
专题	中国科学院海岸带环境过程与生态修复重点实验室中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
通讯作者	Wu, Jun
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Peoples R China 2.Harbin Engn Univ, Yantai Res Inst, Yantai 264006, Peoples R China 3.Guilin Univ Technol, Coll Environm Sci & Engn, Guilin 541006, Peoples R China
推荐引用方式 GB/T 7714	Lu, Jian,Wu, Jun,Zhang, Cui,et al. Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea[J]. FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,2024,18(9):12.
APA	Lu, Jian,Wu, Jun,Zhang, Cui,Wang, Jianhua,&He, Xia.(2024).Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea.FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING,18(9),12.
MLA	Lu, Jian,et al."Occurrence and possible sources of antibiotic resistance genes in seawater of the South China Sea".FRONTIERS OF ENVIRONMENTAL SCIENCE & ENGINEERING 18.9(2024):12.