Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish

doi:10.1038/s41467-024-49848-z

	Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish
	Dong, Zhijun1,2 ; Wang, Fanghan 1,2; Liu, Yali 2,3,4; Li, Yongxue 1,2; Yu, Haiyan 5; Peng, Saijun 1,2; Sun, Tingting 1,2; Qu, Meng 2,3,4; Sun, Ke 6; Wang, Lei1,2 ; Ma, Yuanqing 7; Chen, Kai 6; Zhao, Jianmin1,2 ; Lin, Qiang 2,3,4
发表期刊	NATURE COMMUNICATIONS
	2024-07-15
卷号	15 期号:1 页码:16
DOI	10.1038/s41467-024-49848-z
通讯作者	Dong, Zhijun([email protected]) ; Zhao, Jianmin([email protected]) ; Lin, Qiang([email protected])
英文摘要	Jellyfish exhibit innovative swimming patterns that contribute to exploring the origins of animal locomotion. However, the genetic and cellular basis of these patterns remains unclear. Herein, we generated chromosome-level genome assemblies of two jellyfish species, Turritopsis rubra and Aurelia coerulea, which exhibit straight and free-swimming patterns, respectively. We observe positive selection of numerous genes involved in statolith formation, hair cell ciliogenesis, ciliary motility, and motor neuron function. The lineage-specific absence of otolith morphogenesis- and ciliary movement-related genes in T. rubra may be associated with homeostatic structural statocyst loss and straight swimming pattern. Notably, single-cell transcriptomic analyses covering key developmental stages reveal the enrichment of diapause-related genes in the cyst during reverse development, suggesting that the sustained diapause state favours the development of new polyps under favourable conditions. This study highlights the complex relationship between genetics, locomotion patterns and survival strategies in jellyfish, thereby providing valuable insights into the evolutionary lineages of movement and adaptation in the animal kingdom. Jellyfish represent a critical step in the evolution of early animal movement systems. Here, the authors identify adaptive genetic bases explaining the loss of statocysts in Turritopsis rubra and its ability for reverse development.
资助机构	National Natural Science Foundation of China (National Science Foundation of China) ; National Natural Science Foundation of China ; National Science & Technology Fundamental Resources Investigation Program of China ; National Key Research and Development Program of China ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Taishan Scholars Program ; Seed Project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences
收录类别	SCI
语种	英语
关键词[WOS]	HAIR-CELLS ; CILIARY MOTILITY ; EXPRESSION ; STATOLITH ; BEHAVIOR ; IDENTIFICATION ; PREDICTION ; DIVERSITY ; EVOLUTION ; COMPLEX
研究领域[WOS]	Science & Technology - Other Topics
WOS记录号	WOS:001272555000017
引用统计
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/35661
专题	海岸带生物学与生物资源利用重点实验室支撑部门_中国科学院牟平海岸带环境综合试验站海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Dong, Zhijun; Zhao, Jianmin; Lin, Qiang
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100101, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Peoples R China 4.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510301, Peoples R China 5.Xiamen Univ, Coll Environm & Ecol, Xiamen 361102, Peoples R China 6.Kunming Univ Sci & Technol, Inst Primate Translat Med, State Key Lab Primate Biomed Res, Kunming 650500, Yunnan, Peoples R China 7.Shandong Marine Resource & Environm Res Inst, Shandong Key Lab Marine Ecol Restorat, Yantai 264006, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Dong, Zhijun,Wang, Fanghan,Liu, Yali,et al. Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish[J]. NATURE COMMUNICATIONS,2024,15(1):16.
APA	Dong, Zhijun.,Wang, Fanghan.,Liu, Yali.,Li, Yongxue.,Yu, Haiyan.,...&Lin, Qiang.(2024).Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish.NATURE COMMUNICATIONS,15(1),16.
MLA	Dong, Zhijun,et al."Genomic and single-cell analyses reveal genetic signatures of swimming pattern and diapause strategy in jellyfish".NATURE COMMUNICATIONS 15.1(2024):16.