Enhancing the sensitivity of polymeric membrane polycation-sensitive electrodes by surface modification of a polydopamine nanolayer

doi:10.1016/j.snb.2024.135310

YIC-IR

	Enhancing the sensitivity of polymeric membrane polycation-sensitive electrodes by surface modification of a polydopamine nanolayer
	Wang, Kaikai 1,2,4; Liang, Rongning1,2 ; Qin, Wei1,2,3,5
发表期刊	SENSORS AND ACTUATORS B-CHEMICAL
	2024-04-15
卷号	405 页码:7
关键词	Polymeric membrane ion-selective electrode Polyion-sensitive electrode Polydopamine nanolayer Transmembrane ion flux Enhanced sensitivity
DOI	10.1016/j.snb.2024.135310
通讯作者	Liang, Rongning([email protected]) ; Qin, Wei([email protected])
英文摘要	In this work, a potentiometric polyion sensing strategy based on the surface layer-enhanced transmembrane ion transfer is demonstrated. A polydopamine (PDA) nanolayer with negative charges is modified onto the surface of the polycation-sensitive electrode membrane and used to increase the ion fluxes from the sample phase to the membrane phase. Such modification can significantly improve the detection sensitivity of potentiometric polyion sensors through electrostatic interactions between the cationic targets and anionic PDA groups, which can effectively promote the accumulation of the targets in the boundary layer of the organic membrane phase. By using a thin membrane protamine-sensitive electrode as a model, the detection sensitivity of the PDA-coated electrode (55 mV/mu g & sdot;mL-1) is nearly five times higher than that of the unmodified electrode (12 mV/ mu g & sdot;mL-1). Moreover, the proposed surface PDA-modified polyion sensor can also be utilized as a general tool for sensitive detection of other polycationic targets and polyanionic species (e.g., the new cancer biomarker cell-free DNA). The proposed potentiometric sensing platform based on surface enhancement of ion transfer offers great potential for sensitive detection of various polyionic targets.
资助机构	National Natural Science Foundation of China ; Key Research Development Program of Shandong Province ; Key Deployment Project of Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences ; Taishan Scholar Program of Shandong Province
收录类别	SCI
语种	英语
关键词[WOS]	ION-SELECTIVE ELECTRODES ; ELECTROCHEMICAL SENSOR ; DETECTION LIMITS ; HEPARIN ; MODULATION ; DNA
研究领域[WOS]	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS记录号	WOS:001170706700001
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/34892
专题	中国科学院烟台海岸带研究所
通讯作者	Liang, Rongning; Qin, Wei
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, YICCAS, Yantai 264003, Shandong, Peoples R China 2.Shandong Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Wang, Kaikai,Liang, Rongning,Qin, Wei. Enhancing the sensitivity of polymeric membrane polycation-sensitive electrodes by surface modification of a polydopamine nanolayer[J]. SENSORS AND ACTUATORS B-CHEMICAL,2024,405:7.
APA	Wang, Kaikai,Liang, Rongning,&Qin, Wei.(2024).Enhancing the sensitivity of polymeric membrane polycation-sensitive electrodes by surface modification of a polydopamine nanolayer.SENSORS AND ACTUATORS B-CHEMICAL,405,7.
MLA	Wang, Kaikai,et al."Enhancing the sensitivity of polymeric membrane polycation-sensitive electrodes by surface modification of a polydopamine nanolayer".SENSORS AND ACTUATORS B-CHEMICAL 405(2024):7.