The invention relates to a marine organism inhibitor, and concretely relates to a benzisothiazolinone compound and an application thereof. The benzisothiazolinone compound or a mixture of the benzisothiazolinone compound and a resin is treated as a marine antifouling agent. An N-acyl benzisothiazolinone derivative of the invention can be effectively treated as the antifouling agent for preventing aquatics from adhering to organisms, a fishing net antifouling agent for preventing the organisms which can cause fouling from adhering to and growing on the fixedly arranged fishing net for culture, and the antifouling agent for preventing the fouled organisms from adhering to and growing on bottoms of ships, materials used in fishing nets (buoys and ropes for example), and condensate water channels in nuclear energy/heat energy power plants. The marine antifouling agent of the present invention has no detrimental effect on the storage stability, and does not allow the viscosity to be increased and deterioration to be carried out.
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