The invention relates to the daily chemical field and the pharmaceutical industry, in particular to benzaldehyde Schiff base type aminopyridine acetylated starch and preparation thereof. The structural formula of the benzaldehyde Schiff base type aminopyridine acetylated starch is shown as the formula (1). A preparation method comprises the following steps : firstly, starch reacts with chloroacetyl chloride, then various types of benzaldehyde react with 3-aminopyridine, Schiff bases are prepared, chloroacetyl starch reacts with the prepared Schiff bases finally, and the benzaldehyde Schiff base type aminopyridine acetylated starch shown as the formula (1) is obtained through purification, wherein the molar weight of chloroacetyl chloride is 1-2 times that of the starch, and the molar weight of various types of the Schiff bases is 2-3 times that of the chloroacetyl starch. The reaction is simple, convenient and efficient, popularization is easy, and required equipment and raw materials are easy to obtain. Research proves that the derivative has good water solubility and bacteriostatic activity, the biological activity of the starch is enhanced, the application range of the starch is enlarged, and the starch and the preparation method can be widely applied to the fields of daily chemical and pharmaceuticals.
; 张晶晶; 谭文强
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