The invention relates to fluorescent probes used for detecting superoxide anions (O2.) and bivalent mercury ions (Hg), in particular to fluorophore derivatives and application thereof. For example, the cyanine fluorophore derivatives have a chemical structure as shown in a structural formula I, and the cyanine compounds are taken as fluorescent probes for the O2. and the Hg. The fluorescent probes provided by the invention have the corresponding fluorescence emission wavelength and intensity change in the presence of the O2. and the Hg, can be used for detecting the O2. and the Hg, can greatly reduce the interference of external detection conditions, and is high in detection signal-to-noise ratio and good in sensitivity and selectivity. As the fluorescent probes, the compounds can be used for detecting the levels of the O2. and the Hg in complex biological samples and have important biomedical significance for the study of cell signal transduction of the O2. and the Hg. The structural formula I is described in the description.
; 王悦; 于法标; 高敏
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