The invention relates to a ratio-based monoamine oxidase (MAO) detection fluorescent probe, and particularly relates to an organic compound and application thereof. The compound is as shown in a structural formula I. The compound as the fluorescent probe is used in ratio-detection of MAO on an outer membrane of mitochondrion. The compound is used for detecting MAO based on ratio. When MAO exists, corresponding fluorescent wavelength displaces obviously, so as to be used for MAO detection, interference of an external detection condition is greatly reduced, and the detection accuracy is improved. According to the compound used as the fluorescent probe detecting MAO based on ratio, when MAO exists, ultraviolent absorption changes obviously, and an ultraviolent spectrophotometer and naked eyescan be used for detecting. The compound can be used as a fluorescent probe to detect MAO levels in and out of cells, thereby having biomedical significance in deep research of a manner of catalyzingmonoamine substance through MAO in organisms as well as kinetic mechanisms of production and accumulation of catalyzed products, particularly the physiological action of MAO in the organism and the impact of catalyzed products on life health of the organisms.
; 王蕊; 王猛; 于法标
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