The invention discloses a paper-based device based on a moving valve and a molecular imprinting technology, and a manufacturing method and application thereof
The invention provides a paper-based device based on a moving valve and a molecular imprinting technology as well as a manufacturing method and application thereof. It is characterized by that said preparation method includes the following steps : designing pattern, making chip original component, constructing electrode on paper base, connecting chip original component, synthesizing functionalized molecularly imprinted polymer layer, electrochemical polymerization and eluting template molecule; The device is used for analyzing and detecting biomarkers in a serum sample. The invention has the advantages that : The invention provides a paper-based device based on a moving valve and a molecular imprinting technology as well as a manufacturing method and application thereof. provides a brand-new device for clinical detection of biomarkers, The device is used for synthesizing biomarker molecularly imprinted polymers in situ to form a set of clinical application method, a new strategy of antibody-free biomarker analysis is created, all processes from device manufacturing to detection result output are completed on a paper-based device, and the device has the advantages of economy, portability, rapidness and the like.
; 齐骥; 陈令新
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