The present invention relates to the field of algae inhibitor, and is especially one kind of cadinane derivative from algae endophytic fungi and its preparation process and application in inhibiting algae. The specific structural formula is shown in (I). The preparation method is to inoculate the seaweed endophytic fungus Trichoderma virens (Trichoderma virens) RR-dl-6-8 into a fungal culture medium for fermentation and culture, and the fermentation product is separated and purified to obtain the cadinane derivative shown in formula (I). A microalgae inhibition activity experiment shows that the half inhibition concentration of the compound on microalgae can reach 1.5 micrograms/milliliter.
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