The invention relates to a potential type anti-biological fouling sensor, in particular to a potential type anti-fouling sensor based on indole active substance release and application thereof. A polymer film containing an indole antifouling active substance is coated on the surface of the conductive substrate; The addition amount of the indole antifouling active substance is 0.01-1% of the weight of the polymer film. According to the potential type antifouling sensor based on release of the indole active substances, the antifouling activity of the polymer ion selective electrode can be improved only by doping the indole active substances into the polymer sensitive membrane, and a complex surface chemical modification process is not needed, so that the preparation steps are simplified. Simultaneously, the potential type antifouling sensor based on the indole active substances can continuously, long-term and slowly release the antifouling active substances, The anti-fouling performance of the potential type sensor is realized by means of the inhibition effect of the indole active substances on the growth of fouling organisms and the damage effect on cell biofilms, so that the problem that the potential type sensor is easy to be fouled by organisms when being used in environmental water for a long time is solved. The construction of various antifouling ion-selective electrodes can be realized by changing the types of ion carriers in the ion-selective membrane.
; 秦伟
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