Preparation and Characterization of Chitosan Derivatives Bearing Imidazole Ring with Antioxidant, Antibacterial, and Antifungal Activities

doi:10.1002/star.202200204

	Preparation and Characterization of Chitosan Derivatives Bearing Imidazole Ring with Antioxidant, Antibacterial, and Antifungal Activities
	Ma, Bing 1,2,3; Tan, Wenqiang1,3 ; Zhang, Jingjing 1,3; Mi, Yingqi 1,3; Miao, Qin 1,2,3; Guo, Zhanyong1,2,3
发表期刊	STARCH-STARKE
ISSN	0038-9056
	2023-01-12
页码	13
关键词	antibacterial activity antifungal activity antioxidant activity chitosan derivatives
DOI	10.1002/star.202200204
通讯作者	Guo, Zhanyong([email protected])
英文摘要	In this study, three series of chitosan derivatives bearing imidazole rings, including the Schiff-bases of chitosan, N-substituted chitosan, and quaternized chitosan are designed and synthesized. The structures of these chitosan derivatives are verified by FT-IR and H-1 NMR, and their antioxidant, antibacterial, and antifungal activities are tested. The Schiff-bases of chitosan and N-substituted chitosan have similar biological properties compared with chitosan. Derivatives 2IMTMC, 4IMTMC, MIMTMC, and BIMTMC exhibit significant antioxidant ability and antifungal activity, especially derivative BIMTMC. All the quaternized chitosan remarkably inhibits Escherichia coli, Staphylococcus aureus, and Vibrio harvey, especially derivative BIMTMC, whose minimum inhibitory concentration values are 0.03125, 0.0625, and 0.03125 mg mL(-1), respectively. The results indicated that quaternized chitosan are synergistic with imidazole groups and have the better antioxidant, antifungal, and antibacterial properties than chitosan, which can be used as drug materials for antioxididant and antimicrobial purposes.
资助机构	Key Deployment Project of Center for Ocean Mega-Science of CAS ; Youth Innovation Promotion Association CAS ; 2020 annual Special Research Assistant Project of Chinese Academy of Sciences ; Natural Science Foundation of Shandong Province of China
收录类别	SCI
语种	英语
关键词[WOS]	N-SUBSTITUTED CHITOSAN ; MEMBRANE ; FTIR
研究领域[WOS]	Food Science & Technology
WOS记录号	WOS:000912618600001
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/32589
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Guo, Zhanyong
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Ma, Bing,Tan, Wenqiang,Zhang, Jingjing,et al. Preparation and Characterization of Chitosan Derivatives Bearing Imidazole Ring with Antioxidant, Antibacterial, and Antifungal Activities[J]. STARCH-STARKE,2023:13.
APA	Ma, Bing,Tan, Wenqiang,Zhang, Jingjing,Mi, Yingqi,Miao, Qin,&Guo, Zhanyong.(2023).Preparation and Characterization of Chitosan Derivatives Bearing Imidazole Ring with Antioxidant, Antibacterial, and Antifungal Activities.STARCH-STARKE,13.
MLA	Ma, Bing,et al."Preparation and Characterization of Chitosan Derivatives Bearing Imidazole Ring with Antioxidant, Antibacterial, and Antifungal Activities".STARCH-STARKE (2023):13.