The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts

doi:10.1016/j.carbpol.2021.118970

	The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts
	Mi, Yingqi 1,2,3; Chen, Yuan 4; Tan, Wenqiang1,2 ; Zhang, Jingjing 1,2; Li, Qing1,2 ; Guo, Zhanyong1,2,3
发表期刊	CARBOHYDRATE POLYMERS
ISSN	0144-8617
	2022-02-15
卷号	278 页码:11
关键词	Chitosan quaternary ammonium salts Bioactive anions Schiff base Antifungal activity Antioxidant activity
DOI	10.1016/j.carbpol.2021.118970
通讯作者	Guo, Zhanyong([email protected])
英文摘要	In this study, to investigate the influence of glyoxylate bearing Schiff base on bioactivity to chitosan quaternary ammonium salts, different chitosan derivatives were synthesized by ion exchange of glyoxylate bearing Schiff base with chitosan quaternary ammonium salts (TMCI and HACC). For this purpose, glyoxylate was prepared by Schiff base reaction of glyoxylic acid and amino heterocycles and it was further ionization to substitute iodide ions and chloride ions. After structural characterization by FTIR and H-1 NMR, the antifungal and antioxidant activities were measured. Results indicated that glyoxylate bearing Schiff base could improve the bioactivity of TMCI and HACC obviously. Specifically, anionic TMCI with Schiff base of amino pyridines possessed best antioxidant activity >92.40% at 1.6 mg/mL against DPPH radicals. Meanwhile, they showed antifungal activity >84.88% at 1.0 mg/mL against G. cingulate. Furthermore, the cytotoxicity was evaluated, and all samples showed good cell viability >80.14% at 1000 mu g/mL.
资助机构	National Key Research and Development Program of China ; Youth Innovation Promotion Association CAS ; 2020 Annual Special Research Assistant Project of Chinese Academy of Sciences
收录类别	SCI
语种	英语
关键词[WOS]	DERIVATIVES ; PROPERTY ; DESIGN
研究领域[WOS]	Chemistry ; Polymer Science
WOS记录号	WOS:000760920900008
引用统计	被引频次：27[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/31520
专题	海岸带生物学与生物资源利用重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者	Guo, Zhanyong
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China
推荐引用方式 GB/T 7714	Mi, Yingqi,Chen, Yuan,Tan, Wenqiang,et al. The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts[J]. CARBOHYDRATE POLYMERS,2022,278:11.
APA	Mi, Yingqi,Chen, Yuan,Tan, Wenqiang,Zhang, Jingjing,Li, Qing,&Guo, Zhanyong.(2022).The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts.CARBOHYDRATE POLYMERS,278,11.
MLA	Mi, Yingqi,et al."The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts".CARBOHYDRATE POLYMERS 278(2022):11.