| Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum | |
Shi, Zhen-Zhen1; Liu, Xiang-Hong1,2; Song, Yin-Ping1; Yin, Xiu-Li1 ; Ji, Nai-Yun1
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| 发表期刊 | FITOTERAPIA
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| ISSN | 0367-326X |
| 2021-09-01 | |
| 卷号 | 153页码:5 |
| 关键词 | Trichoderma Sesquiterpenoid Bisabolane Acorane Acyclic sesquiterpenoid Steroid |
| DOI | 10.1016/j.fitote.2021.104983 |
| 通讯作者 | Ji, Nai-Yun([email protected]) |
| 英文摘要 | Six new sesquiterpenoids including three bisabolane derivatives, trichobisabolins O-1, O-2, and P (1-3), two nerolidol derivatives, trichonerolins A and B (4 and 5), one acorane, trichoacorin A (6), along with one new steroid, isoergokonin B (7), were isolated from the culture of Trichoderma brevicompactum A-DL-9-2 obtained from the inner tissue of the red alga Chondria tenuissima. Their structures and relative configurations were assigned by interpretation of 1D/2D NMR and MS data. As acyclic sesquiterpenoids, compounds 4 and 5 were discovered from Trichoderma for the first time. Compounds 1-7 were evaluated for the inhibition of some marine derived organisms, in which, 3 and 4/5 exhibited potent inhibition against Amphidinium carterae and Chattonella marina with IC50 of 1.8 mu g/mL and 1.2 mu g/mL, respectively. In addition, compound 7 could inhibit the growth of Pseudoalteromonas citrea with an MIC value of 64 mu g/mL. |
| 资助机构 | Natural Science Foundation of Shandong Province ; National Natural Science Foundation of China ; Taishan Scholar Project |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | MARINE ; ANTIFUNGAL |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| WOS记录号 | WOS:000684861800026 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/29647 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 |
| 通讯作者 | Ji, Nai-Yun |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Ctr Ocean Mega Sci, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shi, Zhen-Zhen,Liu, Xiang-Hong,Song, Yin-Ping,et al. Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum[J]. FITOTERAPIA,2021,153:5. |
| APA | Shi, Zhen-Zhen,Liu, Xiang-Hong,Song, Yin-Ping,Yin, Xiu-Li,&Ji, Nai-Yun.(2021).Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum.FITOTERAPIA,153,5. |
| MLA | Shi, Zhen-Zhen,et al."Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum".FITOTERAPIA 153(2021):5. |
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| Sesquiterpenoids and（633KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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