Efficient Picosecond Laser for Tattoo Removal in Rat Models

doi:10.12659/MSM.924583

	Efficient Picosecond Laser for Tattoo Removal in Rat Models
	Qu, Yan 1; Wang, Lei2 ; Zhou, Pingyu 1; Zhang, Wei 1
发表期刊	MEDICAL SCIENCE MONITOR
ISSN	1643-3750
	2020-07-25
卷号	26 页码:7
关键词	Laser Therapy Lasers, Dye Skin Abnormalities Tattooing
DOI	10.12659/MSM.924583
通讯作者	Zhou, Pingyu([email protected]) ; Zhang, Wei([email protected])
英文摘要	Background: Tattoos are popular in modern times. Due to the occurance of adverse effects such as poor aesthetic value, scar hyperplasia, and abnormal pigments, there is a high demand for uniform operation standards as well as standards for tattoo technologies. In the present study we used Sprague-Dawley rats to assess the tattoo removal efficacy of use of a picosecond laser at various energy values. Material/Methods: Tattoos were made on the backs of rats, then we used a picosecond laser set at various energy parameters to remove the tattoos. After performing the removal procedure in multiple groups, we selected the most suit-able energy levels with corresponding parameters for the tattoo removal. We recruited human volunteers who wanted their tattoos removed and used the energy level found to perform best during tattoo removal experiments. The tattoo removal effects were evaluated and verified. Four tattoo volunteers were treated by using the optimal energy parameters for picosecond laser technology. Results: Through characterization observation and pathological staining results, it was demonstrated that the 1.9 mJ/mu beam energy laser had the best hollowing effect and the most complete pigment particle crushing effect in the rat skin, and had the best tattoo removal effect. Conclusions: We leveraged the evaluation standard to choose the most suitable energy value of the picosecond laser, which had a good tattoo removal effect and could be employed as a reference for clinical removal of tattoos. This process provides criteria for tattoo removal evaluations as well as alternatives for tattoo removal in clinical practice.
收录类别	SCI
语种	英语
关键词[WOS]	DIFFRACTIVE LENS ARRAY ; ALEXANDRITE LASER ; DUAL-WAVELENGTH ; SAFETY ; EFFICACY ; NDYAG ; VI
研究领域[WOS]	Research & Experimental Medicine
WOS记录号	WOS:000552228400001
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/28584
专题	中国科学院烟台海岸带研究所知识产出中国科学院烟台海岸带研究所
通讯作者	Zhou, Pingyu; Zhang, Wei
作者单位	1.Tongji Univ, Shanghai Skin Dis Hosp, Sch Med, Shanghai, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Qu, Yan,Wang, Lei,Zhou, Pingyu,et al. Efficient Picosecond Laser for Tattoo Removal in Rat Models[J]. MEDICAL SCIENCE MONITOR,2020,26:7.
APA	Qu, Yan,Wang, Lei,Zhou, Pingyu,&Zhang, Wei.(2020).Efficient Picosecond Laser for Tattoo Removal in Rat Models.MEDICAL SCIENCE MONITOR,26,7.
MLA	Qu, Yan,et al."Efficient Picosecond Laser for Tattoo Removal in Rat Models".MEDICAL SCIENCE MONITOR 26(2020):7.

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