| New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities | |
Mi, Yingqi1,2,3; Zhang, Jingjing1,2,3; Chen, Yuan1,2,3; Sun, Xueqi1,2,3; Tan, Wenqiang1,2 ; Li, Qing1,2; Guo, Zhanyong1,2,3
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| 发表期刊 | CARBOHYDRATE POLYMERS
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| ISSN | 0144-8617 |
| 2020-12-01 | |
| 卷号 | 249页码:8 |
| 关键词 | Carboxymethyl chitosan Heterocyclic compounds Antifungal activity Antioxidant activity Cytotoxicity assay |
| DOI | 10.1016/j.carbpol.2020.116847 |
| 通讯作者 | Guo, Zhanyong([email protected]) |
| 英文摘要 | In this paper, several novel chitosan derivatives bearing benzenoid / heterocyclic moieties were synthesized via introducing aminobenzene and heterocyclic compounds onto carboxymethyl chitosan. The specific structures of chitosan derivatives were confirmed by FTIR, H-1 NMR, and elemental analysis. Meanwhile, the antioxidant efficiencies of chitosan derivatives were assayed in vitro. In particular, all chitosan derivatives showed significant improvement in superoxide-radical scavenging activity and DPPH radical scavenging activity. Their antifungal activities against two plant pathogenic fungi (Colletotrichum lagenarium and Phomopsis asparagi) were estimated in vitro by hyphal measurement, and all products exhibited excellent antifungal activity. Besides, the cytotoxicity of them was also measured by CCK-8 in vitro on L929 cells, and all samples showed low cytotoxicity. The good biocompatibility and enhanced biological activity of new synthetic chitosan derivatives might be obvious ad-vantages, while applied in wide range of applications as antifungal agents or antioxidants in food, medicine, cosmetics, and other fields. |
| 资助机构 | National Key R&D Program of China ; Key R&D Program of Shandong Province ; Natural Science Foundation of Shandong Province of China |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | IN-VITRO ; NANOPARTICLES ; BASES ; ACID ; NMR |
| 研究领域[WOS] | Chemistry ; Polymer Science |
| WOS记录号 | WOS:000571541800001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/28400 |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Guo, Zhanyong |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mi, Yingqi,Zhang, Jingjing,Chen, Yuan,et al. New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities[J]. CARBOHYDRATE POLYMERS,2020,249:8. |
| APA | Mi, Yingqi.,Zhang, Jingjing.,Chen, Yuan.,Sun, Xueqi.,Tan, Wenqiang.,...&Guo, Zhanyong.(2020).New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities.CARBOHYDRATE POLYMERS,249,8. |
| MLA | Mi, Yingqi,et al."New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities".CARBOHYDRATE POLYMERS 249(2020):8. |
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| New synthetic chitos（1717KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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