Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives

doi:10.3390/polym12010112

YIC-IR > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives
	Chen, Yuan ; Liu, Xiguang ; Sun, Xueqi ; Zhang, Jingjing ; Mi, Yingqi ; Li, Qing; Guo, Zhanyong
发表期刊	POLYMERS
	2020-01
卷号	12 期号:1 页码:112
关键词	CHITOSAN DERIVATIVES CLICK REACTION POLYSACCHARIDE
研究领域	Polymer Science
DOI	10.3390/polym12010112
产权排序	[Chen, Yuan; Liu, Xiguang] Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China; [Chen, Yuan; Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Chen, Yuan; Sun, Xueqi; Zhang, Jingjing; Mi, Yingqi; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者	Guo, Zhanyong([email protected])
作者部门	海岸带生物资源高效利用研究与发展中心
英文摘要	In this study, starch was chemically modified to improve its antioxidant activity. Five novel cationic 1,2,3-triazole functionalized starch derivatives were synthesized by using "click" reaction and N-alkylation. A convenient method for pre-azidation of starch was developed. The structures of the derivatives were analyzed using FTIR and H-1 NMR. The radicals scavenging abilities of the derivatives against hydroxyl radicals, DPPH radicals, and superoxide radicals were tested in vitro in order to evaluate their antioxidant activity. Results revealed that all the cationic starch derivatives (2a-2e), as well as the precursor starch derivatives (1a-1e), had significantly improved antioxidant activity compared to native starch. In particular, the scavenging ability of the derivatives against superoxide radicals was extremely strong. The improved antioxidant activity benefited from the enhanced solubility and the added positive charges. The biocompatibility of the cationic derivatives was confirmed by the low hemolytic rate (<2%). The obtained derivatives in this study have great potential as antioxidant materials that can be applied in the fields of food and biomedicine.
文章类型	Article
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156] ; National Key R&D Program of China [2019YFD0900705] ; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2017BD015] ; Science and Technology Service Network Initiative of Chinese academy of sciences [KFJ-STS-ZDTP-023] ; Public Science and Technology Research Funds Projects of Ocean [2015418022-3] ; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences [YIC Y755031011]
收录类别	SCI
语种	英语
关键词[WOS]	CHITOSAN DERIVATIVES ; CLICK REACTION ; POLYSACCHARIDE
研究领域[WOS]	Polymer Science
WOS记录号	WOS:000519848300112
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/25100
专题	海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位	1.Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China; 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Yuan,Liu, Xiguang,Sun, Xueqi,et al. Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives[J]. POLYMERS,2020,12(1):112.
APA	Chen, Yuan.,Liu, Xiguang.,Sun, Xueqi.,Zhang, Jingjing.,Mi, Yingqi.,...&Guo, Zhanyong.(2020).Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives.POLYMERS,12(1),112.
MLA	Chen, Yuan,et al."Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives".POLYMERS 12.1(2020):112.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Synthesis and Antiox（4293KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览请求全文