Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis

doi:10.1016/j.etap.2019.03.004

	Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis
	Zhu, N ; Yang, YY ; Xu, H ; Wang, Q; Wei, YY ; Li, MZ ; Li, F; Wang, YQ; Zhang, HW ; Liu, YH ; Wang, XM ; Fang, Y
发表期刊	ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
ISSN	1382-6689
	2019-05
卷号	68 页码:19-26
关键词	Decabromodiphenyl ether Antioxidant enzymes Bioaccumulation Mactra venerifonnis
研究领域	Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology
DOI	10.1016/j.etap.2019.03.004
产权排序	[Zhu, Na; Wei, Yanyan; Li, Mingzhu; Wang, Yiqi; Wang, Xiaomeng; Fang, Yan] Ludong Univ, Sch Agr, Yantai 264025, Peoples R China; [Yang, Yanyan; Li, Fan; Zhang, Huawei; Liu, Yihao] Shandong Marine Resource & Environm Res Inst, Shandong Prov Key Lab Restorat Marine Ecol, Yantai 264006, Peoples R China; [Xu, Hua] Yantai Environm Monitoring Ctr, Yantai 264000, Peoples R China; [Wang, Qing] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
通讯作者	Fang, Yan([email protected])
作者部门	海岸带生物资源高效利用研究与发展中心
英文摘要	Antioxidant enzymes play vital roles against oxidative stress induced by decabromodiphenyl ether (BDE-209), being widespread in marine environment. However, the effect of BDE-209 on antioxidant enzymes remains poorly understood in marine bivalves. In this study, the clams Mactra veneriformis were exposed to 0.1, 1, and 10 mu g/L BDE-209 for 7 days and then maintained in clean seawater for 3 days as the depuration. The bioaccumulation of BDE-209 and the effects on superoxide dismutase, catalase, and glutathione peroxidase were investigated. BDE-209 accumulation was concentration-dependent and decreased by 36%-52% after recovery. Malondialdehyde contents increased in a time- and dose-dependent manner. mRNA expression and activity of antioxidant enzymes changed with different patterns and recovered after depuration. These results suggested that antioxidant systems were triggered to protect the clams from oxidative damage caused by BDE-209. Thus, this research is helpful in elucidating the effect of BDE-209 on antioxidant system in marine bivalves.
文章类型	Article
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41206120, 31502173] ; Development Plan of Science and Technology in Yantai [2011062] ; Ludong University Research Funding [210-32040301] ; Innovative Project of Undergraduate [201710451330, 201710451331, 201710451332] ; Marine and Fisheries Science and Technology Innovation Program of Shandong Province [2017YY04]
收录类别	SCI
语种	英语
关键词[WOS]	POLYBROMINATED DIPHENYL ETHERS ; MUSSEL WATCH PROGRAM ; PEARL RIVER DELTA ; OXIDATIVE STRESS ; MOLECULAR-CLONING ; PRENATAL TRANSFER ; DIGESTIVE GLAND ; ENZYME-ACTIVITY ; PACIFIC OYSTER ; LEAD TOXICITY
研究领域[WOS]	Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology
WOS记录号	WOS:000467667300004
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/24945
专题	中国科学院海岸带环境过程与生态修复重点实验室海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
作者单位	1.Ludong Univ, Sch Agr, Yantai 264025, Peoples R China; 2.Shandong Marine Resource & Environm Res Inst, Shandong Prov Key Lab Restorat Marine Ecol, Yantai 264006, Peoples R China; 3.Yantai Environm Monitoring Ctr, Yantai 264000, Peoples R China; 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Zhu, N,Yang, YY,Xu, H,et al. Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2019,68:19-26.
APA	Zhu, N.,Yang, YY.,Xu, H.,Wang, Q.,Wei, YY.,...&Fang, Y.(2019).Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,68,19-26.
MLA	Zhu, N,et al."Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 68(2019):19-26.

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