| Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives | |
Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang ; Chen, Yuan; Wang, Ping; Dong, Fang; Li, Qing; Guo, Zhanyong
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| 发表期刊 | STARCH-STARKE
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| ISSN | 0038-9056 |
| 2018-11 | |
| 卷号 | 70期号:11-12页码:1800026 |
| 关键词 | antifungal activity N-diquaternized chitin N-quaternized chitin quaternary ammonium salt |
| 研究领域 | Food Science & Technology |
| DOI | 10.1002/star.201800026 |
| 产权排序 | [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Wang, Ping] Binzhou Med Univ Hosp, Dept Infect Dis, Binzhou 256603, Peoples R China |
| 作者部门 | 海岸带生物资源高效利用研究与发展中心 |
| 英文摘要 | To improve the bioactivity of chitin (CT), novel N-quaternized (QCT), and N-diquaternized (DQCT) CT derivatives are synthesized through a series of reactions from CT. The derivatives are characterized using elemental analysis, FTIR, and C-13 NMR. In addition, the inhibitory effects of the compounds against three fungi (B. cinerea, F. oxysporum, and P. asparagi) are tested. The inhibitory indices of CT, QCT, and DQCT are 12-15%, 63-73%, and 74-89%, respectively, at 1.0 mg mL(-1). The antifungal activities are in the order of DQCT > QCT > CT, which correlated with the number of quaternized groups. Based on these results, it is concluded that the antifungal activity of CT is improved by the introduction of quaternized groups on CT backbone. |
| 文章类型 | Article |
| 资助机构 | National Natural Science Foundation of China [41576156] ; Natural Science Foundation of Shandong Province of China [ZR2017BD015] ; Yantai Science and Technology Development Plan [2015ZH078, 2015418022-3] ; Technology Research Funds Projects of Ocean [2015418022-3] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | FACILE CHEMICAL-MODIFICATIONS ; CHITOSAN DERIVATIVES ; ANTIBACTERIAL ACTIVITY ; ANTIOXIDANT ACTIVITIES ; ANTIMICROBIAL ACTIVITY ; BETA-CHITIN ; IN-VITRO ; EXTRACTION ; PRECURSORS |
| 研究领域[WOS] | Food Science & Technology |
| WOS记录号 | WOS:000449763300030 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24564 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 3.Binzhou Med Univ Hosp, Dept Infect Dis, Binzhou 256603, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luan, Fang,Wei, Lijie,Zhang, Jingjing,et al. Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives[J]. STARCH-STARKE,2018,70(11-12):1800026. |
| APA | Luan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives.STARCH-STARKE,70(11-12),1800026. |
| MLA | Luan, Fang,et al."Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives".STARCH-STARKE 70.11-12(2018):1800026. |
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