| Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity | |
Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang ; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong
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| 发表期刊 | MOLECULES
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| ISSN | 1420-3049 |
| 2018-03 | |
| 卷号 | 23期号:3页码:516 |
| 关键词 | cationic chitosan derivatives quaternized chitosan double quaternized chitosan antioxidant ability |
| 研究领域 | Biochemistry & Molecular Biology ; Chemistry |
| DOI | 10.3390/molecules23030516 |
| 产权排序 | [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Shangdong, Peoples R China; [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 作者部门 | 海岸带生物学与生物资源保护实验室 |
| 英文摘要 | Chitosan (CS) is an abundant and renewable polysaccharide that is reported to exhibit a great variety of beneficial properties. However, the poor solubility of chitosan in water limits its applications. In this paper, we successfully synthesized single N-quaternized (QCS) and double N-diquaternized (DQCS) chitosan derivatives, and the resulting quaternized materials were water-soluble. The degree of quaternization (DQ) of QCS and DQCS was 0.8 and 1.3, respectively. These derivatives were characterized by FTIR, H-1 NMR, C-13 NMR, TGA, and SEM. Moreover, the antioxidant activity of the chitosan was evaluated by free radical scavenging ability (against DPPH-radical, hydroxyl-radical, and superoxide-radical) and ferric reducing power. Our results suggested that the antioxidant abilities were in the order of DQCS > QCS > CS, which was consistent with the number of quaternized groups. These data demonstrate that the number of quaternized groups of chitosan derivatives contributes to their antioxidant activity. Therefore, DQCS, with a higher number of quaternized groups and higher positive charge density, is endowed with high antioxidant activity, and can be used as a candidate material in food and pharmaceutical industries. |
| 文章类型 | Article |
| 资助机构 | Natural Science Foundation of China [41576156] ; Shandong Province Science and Technology Development Plan [2015GSF121045] ; Yantai Science and Technology Development Plan [2015ZH078] ; Technology Research Funds Projects of Ocean [2015418022-3] |
| 收录类别 | SCI |
| 语种 | 英语 |
| 关键词[WOS] | ANTIBACTERIAL ACTIVITY ; CHEMICAL-MODIFICATIONS ; SCAVENGING ACTIVITY ; TRIMETHYL CHITOSAN ; AMMONIUM CHITOSAN ; CHITIN ; EXTRACTION ; HYDROGELS ; CHLORIDE |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
| WOS记录号 | WOS:000428514100007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.yic.ac.cn/handle/133337/24496 |
| 专题 | 海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室 中国科学院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室 海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Shangdong, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luan, Fang,Wei, Lijie,Zhang, Jingjing,et al. Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity[J]. MOLECULES,2018,23(3):516. |
| APA | Luan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity.MOLECULES,23(3),516. |
| MLA | Luan, Fang,et al."Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity".MOLECULES 23.3(2018):516. |
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