Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma | |
Zhang, Yong1; Hu, Xiaoyan1; Hu, Yue1; Teng, Kai2; Zhang, Kai1; Zheng, Yamei3; Hong, Xiaohua1; Yu, Kunwu4; Wang, Yan5; Liu, Li1 | |
发表期刊 | JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH |
ISSN | 1756-9966 |
2015-02-05 | |
卷号 | 34 |
关键词 | E-cadherin Dendritic Cell t Cell Lung Cancer Activity |
DOI | 10.1186/s13046-015-0126-9 |
英文摘要 | Background: Agonistic CD40 antibodies have been demonstrated to activate antigen-presenting cells (APCs) and enhance antitumour T cell responses, thereby providing a new therapeutic option in cancer immunotherapy. In agonistic CD40 antibody-mediated inflammatory responses, a novel subset of E-cadherin + dendritic cells (DCs) has been identified, and little is known about the role of these DCs in tumour immunity. This study investigated the effect of anti-CD40-mediated inflammatory E-cadherin + DCs in murine Lewis lung carcinoma (LLC). |
文章类型 | Article |
资助机构 | National Natural Science Foundations of China(81171979, 81372260) ; Doctoral fund(20110142110005) |
收录类别 | SCI |
语种 | 英语 |
关键词[WOS] | IN-VIVO ; TUMOR-GROWTH ; LYMPH-NODES ; CANCER ; CD40 ; THERAPY ; MICE ; DIFFERENTIATION ; IMMUNOTHERAPY ; POPULATION |
研究领域[WOS] | Oncology |
WOS记录号 | WOS:000350440200001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.yic.ac.cn/handle/133337/24040 |
专题 | 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心 中国科学院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室 |
通讯作者 | Liu, Li |
作者单位 | 1.Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Canc, Wuhan 430023, Hubei, Peoples R China 2.Hainan Canc Hosp, Haikou, Hainan, Peoples R China 3.Cent Hosp Wuhan, Dept Oncol, Wuhan, Hunan, Peoples R China 4.Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Inst Cardiol,Lab Cardiovasc Immunol, Wuhan 430023, Hubei, Peoples R China 5.Chinese Acad Sci, Anal & Testing Ctr, Inst Hydro Biol, Wuhan, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Yong,Hu, Xiaoyan,Hu, Yue,et al. Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma[J]. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,2015,34. |
APA | Zhang, Yong.,Hu, Xiaoyan.,Hu, Yue.,Teng, Kai.,Zhang, Kai.,...&Liu, Li.(2015).Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma.JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH,34. |
MLA | Zhang, Yong,et al."Anti-CD40-induced inflammatory E-cadherin plus dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma".JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 34(2015). |
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