Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium

doi:10.1007/s10646-016-1741-8

	Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium
	Wu, Huifeng; Xu, Lanlan ; Yu, Deliang ; Ji, Chenglong; Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. [email protected]
发表期刊	ECOTOXICOLOGY
ISSN	0963-9292
	2017
卷号	26 期号:1 页码:74-80
关键词	Mytilus Galloprovincialis Cadmium Toxicological Effects Nmr Metabolomics
DOI	10.1007/s10646-016-1741-8
产权排序	[Wu, Huifeng; Xu, Lanlan; Yu, Deliang; Ji, Chenglong] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Xu, Lanlan; Yu, Deliang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门	中科院海岸带环境过程与生态修复重点实验室
英文摘要	Cadmium (Cd) is one of the most important metal contaminants in the Bohai Sea. In this work, NMR-based metabolomics was used to investigate the toxicological effects of Cd at an environmentally relevant concentration (50 A mu g L-1) in three different life stages (D-shape larval, juvenile and adult) of mussels Mytilus galloprovincialis. Results indicated that the D-shape larval mussel was the most sensitive life stage to Cd. The significantly different metabolic profiles meant that Cd induced differential toxicological effects in three life stages of mussels. Basically, Cd caused osmotic stress in all the three life stages via different metabolic pathways. Cd exposure reduced the anaerobiosis in D-shape larval mussels and disturbed lipid metabolism in juvenile mussels, respectively. Compared with the D-shape larval and juvenile mussels, the adult mussels reduced energy consumption to deal with Cd stress.
文章类型	Article
资助机构	NSFC(41676114) ; Natural Science Foundation of Shandong Province(JQ201310)
收录类别	SCI
语种	英语
关键词[WOS]	METABONOMICS ; SUCCINATE ; POLLUTION ; ALANINE ; COPPER ; GILLS ; WATCH
研究领域[WOS]	Environmental Sciences & Ecology ; Toxicology
WOS记录号	WOS:000393028400007
引用统计	被引频次：26[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.yic.ac.cn/handle/133337/20234
专题	中国科学院海岸带环境过程与生态修复重点实验室
通讯作者	Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. [email protected]
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc,YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wu, Huifeng,Xu, Lanlan,Yu, Deliang,et al. Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium[J]. ECOTOXICOLOGY,2017,26(1):74-80.
APA	Wu, Huifeng,Xu, Lanlan,Yu, Deliang,Ji, Chenglong,&Wu, HF .(2017).Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium.ECOTOXICOLOGY,26(1),74-80.
MLA	Wu, Huifeng,et al."Differential metabolic responses in three life stages of mussels Mytilus galloprovincialis exposed to cadmium".ECOTOXICOLOGY 26.1(2017):74-80.

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